Book with us
—up to 10% cheaper
than on Booking.com
Check rooms and rates
From159US$ /night
Check-in
27Nov2025Select date
Check-out
28Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

350 North Main Street, Greenville, South Carolina, United States, 29601
Perfect
9.0
9.0
/10
4.4
3.9
/5

The comfortable Home2 Suites By Hilton Greenville Downtown hotel is around 25 minutes' walk from the zoological park "Greenville Zoo" and has an outdoor swimming pool and a gym. Located within a few blocks of Piazza Bergamo, this 3-star smoke-free hotel also offers proximity to the Dark Corner Distillery.

Location

You'll need 24-minute drive to Greenville-Spartanburg International airport. The Liberty Bridge is a mere 1.3 km from the Home2 Suites Greenville, while Towers East Apts bus stop is merely 0.7 km away.

The West End is nearly 15 minutes' walk away, while Greenville County Art Museum is situated within reach of the hotel.

Rooms

Some of the air-conditioned rooms are equipped with blackout curtains and an ironing board, as well as media facilities such as free wireless internet. For your comfort, you will find a full-sized refrigerator, kitchenware, and a dishwasher.

Eat & Drink

Soby's is 250 metres from Home2 Suites By Hilton Greenville Downtown hotel and specialises in American cuisine.

Leisure & Business

Guests can relax and entertain with a shared lounge and barbecue grills. There are a business centre with a work desk and complimentary wireless internet access available on site.

View all

Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Studio Suite Two Queen Beds Hearing Access or Non-Smoking
2 persons
30 m² 
1 King-size bed
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
30 m² 
1 King-size bed
Heating
Air conditioning
King Studio Suite Mobility Access or Non-Smoking
2 persons
30 m² 
1 King-size bed
Heating
Air conditioning
King Suite Mobility Access or Non-Smoking
2 persons
30 m² 
1 King-size bed and 1 Sofa bed
Heating
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Rates & availability calendar

See current prices and availability for your chosen dates!

Local transport and travel tips

Overview of transport options available

City Centre
Greenville400 m
Airports
Greenville-Spartanburg International (GSP) 22.4 km
Asheville Regional (AVL) 78.0 km
Train
Greenville County Art Museum400 m

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • Fireplace

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Laundry

Business

  • Business centre

Spa & Leisure

  • Outdoor swimming pool
  • Sun loungers
  • Sun terrace
  • BBQ facilities
  • Leisure/ TV room

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Garden furniture
  • Ironing facilities

Self-catering

  • Cookware/ Kitchen utensils
Show more

Hotel location

350 North Main Street, Greenville, South Carolina, United States, 29601
Map view
350 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
360 m
Event hall
Kilgore Lewis House
340 m
Hockey Stadium
Bon Secours Wellness Arena
580 m
14 S Main St
Dark Corner Distillery
510 m
Gallery
The Art Cellar
170 m
220 N Main St
Noma Square
180 m
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
530 m
Museum
Sigal Music Museum
560 m
Gallery
Artists Guild Gallery Of Greenville
220 m
430 N Main St
American Legion
260 m
Restaurants
Jersey Mike's Subs
170 m
233 N Main St Suite 10
Subway
240 m
225 N Main St
Antonino Bertolo's Pizza and Wine Bar
230 m
200 N Main St Ste 103
Maple Street Biscuit Company- Downtown Greenville
320 m
18 E North St
Coffee Underground
370 m
1 East Coffee Street
Sharkey's Pub
310 m
112 N Main St
Vic's Pizza
390 m
12 E Coffee St
Groucho's Deli
430 m
20 E Coffee St # SC
Want access to early-bird pet-friendly hotel deals?
Access exclusive discounts today!
Check Rates

Next best alternative

Consider them for your next trip.
Check-in
27Nov2025Select date
Check-out
28Nov2025Select date
Rooms and Guests2 Guests, 1 Room